1H-Pyrrolo[2,3-b]pyridine-2-carboxylicacid, 5-chloro-, Methyl ester - Names and Identifiers
Name | methyl 5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate
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Synonyms | Methyl 5-chloro-1H-pyrrolo[2 Methyl 5-chloro-7-azaindole-2-carboxylate Methyl 5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate methyl 5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate Methyl 5-chloro-1H-pyrrolo[2,3-b]pyridine-2- carbo×ylate 5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester 1H-Pyrrolo[2,3-b]pyridine-2-carboxylicacid, 5-chloro-, Methyl ester
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CAS | 952182-19-3
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InChI | InChI=1/C9H7ClN2O2/c1-14-9(13)7-3-5-2-6(10)4-11-8(5)12-7/h2-4H,1H3,(H,11,12) |
1H-Pyrrolo[2,3-b]pyridine-2-carboxylicacid, 5-chloro-, Methyl ester - Physico-chemical Properties
Molecular Formula | C9H7ClN2O2
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Molar Mass | 210.62 |
Density | 1.453g/cm3 |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.657 |
1H-Pyrrolo[2,3-b]pyridine-2-carboxylicacid, 5-chloro-, Methyl ester - Introduction
methyl 5-choro-1H-chrrolo [2,3-b]pyridine-2-carboxylate is an organic compound with the chemical formula C11H7ClN2O2. It is a colorless to light yellow solid with special chemical properties and structural characteristics.
The following is a detailed description of the nature, use, preparation and safety information of methyl 5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate:
Nature:
-Appearance: Colorless to light yellow solid
-melting point: 78-83 ℃
-Boiling point: 380.4 ℃
-Molecular weight: 246.64g/mol
-Solubility: Soluble in organic solvents such as alcohols, ketones and esters, slightly soluble in water
Use:
- methyl 5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate is commonly used as an intermediate in organic synthesis and can be used to prepare various organic compounds.
-It also has certain applications in the field of pesticides, and can be used as raw materials for pesticides, fungicides, etc.
Preparation Method:
The preparation of-methyl 5-choro-1H-prrolo [2,3-b]pyridine-2-carboxylate is generally achieved by chemical synthetic methods.
-The specific preparation steps include: firstly, pyrrolo [2,3-B] pyridine, thionyl chloride and trimethyl alumina are mixed, and reacted under suitable conditions to obtain the target product.
Safety Information:
- methyl 5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carboxylate is relatively safe under normal circumstances, but there may be certain potential hazards.
-When handling the compound, wear appropriate protective equipment, such as laboratory gloves, goggles and laboratory coats, to avoid contact with skin, eyes and mouth.
-In case of inadvertent contact, flush the affected area promptly with plenty of water and seek medical advice.
-During storage and handling, pay attention to prevent contact with incompatible substances such as oxidants, acids and high temperatures to avoid accidents.
Last Update:2024-04-10 22:29:15